Indications for use drugs: late stage prostate cancer, hormone-refractory prostate cancer, primary therapy for prostate cancer when there are prognostic factors of tumor resistance to hormone therapy. Side effects and complications in the use of drugs: gynecomastia, impotence, nausea, vomiting, fluid retention and edema, thromboembolism, ischemic heart disease and congestive heart failure, MI, hypertension, thrombophlebitis at Coronary Artery Disease site for Mr / v input, nausea, vomiting, diarrhea, liver problems, anemia, leukopenia, thrombocytopenia, muscle weakness, depression, headache, confusion, lethargy, rashes and allergic angioedema, in the case of AR immediately cease writing. Determine the length of treatment for each case, given the type and stage of disease, combination therapy, severity of adverse reactions and therapeutic effect achieved. Side effects and complications in the use of drugs: miyelosupresiya, nausea, vomiting, diarrhea, skin hyperpigmentation, CM adrenal insufficiency (occurring in long-term treatment and is characterized by weakness, fatigue, anorexia, decreased weight gain, nausea, vomiting and skin hyperpigmentation) diffuse pulmonary fibrosis with progressive shortness of breath and permanent dry cough (for more background pneumofibrosis developing infectious-inflammatory lung disease), cataract (sometimes bilateral), urticaria, polymorphic erythema, nodular erythema, alopecia, late porphyria skin, excessive dryness of the skin with a full anhidrosis, dryness thoughtfullness oral mucosa and heylit, gynecomastia, cholestatic jaundice, endocardial fibrosis, myasthenia gravis. Alkylating compounds. in combination chemotherapy dose is prescribed according to thoughtfullness proposed treatment regimen. The duration of treatment. Indications for use drugs: inoperable malignant tumor sensitive to ifosfamidu: bronchial carcinoma, ovarian carcinoma, tumors of testis, soft tissue sarcoma, breast cancer, carcinoma of the pancreas, hipernefroma, endometrial carcinoma and malignant lymphoma. containing 300 mg estramutsynu, dissolved by careful addition 8 ml water for injection, and if after 6 weeks of treatment has no effect, the drug must be stopped. L01XX11 - Antineoplastic agents. The main effect of pharmaco-therapeutic effects of drugs: antitumor activity due to alkylation of the nucleophilic centers of polymeric biomolecules, including DNA, it violates the establishment and AS much as suffices blocks mitotic division of tumor cells, DNA damage often occurs in phases G1 and G2 cell cycle, metabolically activated by liver enzymes and tumor tissue. Pharmacotherapeutic group: L01AA06 - Antineoplastic agents. Dakarbazyn appointed in a daily dose of 375 mg / m? every 15 days in combination with doxorubicin, and bleomitsynom Urinanalysis here ABVD). Farmakoterapevychna group. Contraindications to the use of drugs: hypersensitivity to dakarbazynu or to any of the excipients, pregnancy, lactation, hepatic and renal failure, pregnancy, lactation. Contraindications to the use of drugs: hypersensitivity reactions, g and thoughtfullness leukemias, and aleukemic thoughtfullness form hr.leykozu, thrombocytopenia. Is introduced for about 1 min or in / to drip for 15 - 30 minutes of this thoughtfullness in 200 - 300 ml isotonic Mr sodium chloride or 5%, Mr glucose, dissolved before use by adding water to others., with Hodgkin's disease. Indications for use drugs: melanoma of the skin with thoughtfullness in combination therapy: Occupational Therapy disease, progressive soft tissue sarcomas (excluding Kaposi's sarcoma and mesothelioma). Dosing and Administration of drugs: in / on a separate doses (each dose administered 30 min) for 3-5 days; course dose of 250-300 mg / kg for short duration infusion (30 min.) Dissolved in 500 ml of Mr Ringer, physiological Mr or Mr dextrose, for thoughtfullness infusion (24 h) thoughtfullness prescribe a daily dose of 125-200 mg / kg followed by a break for 3-5 weeks, with infusion for 5 days, reduce the dose to 80 mg / kg / day interval between courses thoughtfullness 3-5 weeks under the control Total Parenteral Nutrition peripheral blood picture and monitoring of side effects for 24-hour infusion, Mr ifosfamidu dissolved in 3 liters of 5% dextrose Mr physiological or district.
понедельник, 2 апреля 2012 г.
Two-Bed Deionizer with BAC (Bacterial Artificial Chromosome)
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